Psychosis

PPiP2

Calling for participants until

30 Nov 2027

Participant type

16 - 70 year olds

Rewards

£10 voucher for taking part

Overview

This study aims to see how many people with psychosis may have a specific problem with their immune system. We can find out that by testing your blood sample for specific antibodies.

Summary

There is some evidence that some cases of psychosis may be caused by a specific problem with the immune system. The immune system normally controls our ability to fight infection. If the immune system goes wrong it may cause condition called 'autoimmune' diseases. We can diagnose some of these diseases using blood tests.

This study aims to see how many people with psychosis may have this specific problem with their immune system. We can find out that by testing your blood sample for specific antibodies.

If a problem with immune system is found, then you may be eligible to take part in a study called SINAPPS2.

For more information, please take a look at the study website: https://www.psych.ox.ac.uk/research/autoimmune-psychosis/pippa2-summary

Male or female

16- 70 years old

Psychotic symptoms (psychotic symptoms in current episode lasting for more than 2 weeks, less than 2 years)

You are also able to take part if you don't have capacity, as long as your nearest relative/named clinician or consultant is happy to consent on your behalf

You may not be able to take part if you have: any other illnesses that affect the brain or nerves, such as multiple sclerosis, epilepsy, stroke, fluid on the brain, brain injury, or brain infection. This also includes lupus or blood vessel problems in the brain, and mental health problems caused directly by drugs

Meet the researcher

Sam Heathcote

Sam Heathcote is a Senior Research Practitioner at Devon Partnership NHS Trust and a qualified social worker with over 25 years' experience in adult mental health. She has worked across diverse settings, including MIND, Assertive Outreach, specialist personality disorder services and as an approved mental health professional. Sam spent a decade in a community mental health team and brings strong clinical expertise and risk management skills to her role. Within the Research and Development team, she recruits study participants and supports data collection, contributing her experience and insight to help deliver meaningful, high-quality mental health research.

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Collaborators

University Of Oxford logo Devon Partnership NHS Trust logo