Dementias and neurodegeneration,Healthy volunteers
ON FIRE Study
Calling for participants until
01 Nov 2027
Participant type
Adults
Rewards
N/A
Overview
The ON FIRE study is looking at inflammation in people with confirmed or suspected Frontotemporal dementias, including progressive aphasia and health volunteers.
Summary
This study looks at Frontotemporal dementia, which comes in many different types.
It is made worse by brain inflammation, which has been shown with brain scans and blood tests. But we do not know enough about the differences between people with Frontotemporal dementia, or how well the new blood tests work in different clinical settings and with people of different backgrounds.
Blood tests for inflammation are a good way to find out more about how the disease progresses, but we need to discover the best tests and learn how they work in different people. This study will find the best way to measure inflammation in people with Frontotemporal dementia, and its causes.
The study will bring together different types of researchers and share research knowledge to speed up progress in the diagnosis and treatment of people with Frontotemporal dementia.
If you would like any further information, please contact dpt.researchadmin@nhs.net or call 01392 674117
You can take part if you have been diagnosed with or are being investigated for any type of Frontotemporal dementia, including behavioural variant (bvFTD) and primary progressive aphasia (PPA).
We are also looking for healthy volunteers to take part.
Patients with diagnosis:
Not willing to have blood tests
Lack capacity to provide informed consent and no trusted person who can help provide consent is identified i.e. family member, carer or friend
Healthy Volunteers:
Presence of significant medical illness that would affect your ability to take part
Not willing to have a blood tests
Unable to consent
Meet the researcher
Angie HollandAngie Holland is a Registered Mental Health Nurse at Devon Partnership NHS Trust with experience in older people's mental health. She is passionate about improving diagnosis, treatment and care for people with dementia and cognitive impairment. Angie believes that those with lived experience should guide decisions in care, policy and research. Since 2022 she has worked on a range of dementia studies and completed the Chief Nurse Research Fellow Program. She is committed to promoting dignity, person-centred care and meaningful inclusion, while making research accessible to all.
Collaborators
