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Study outcomes

If you have taken part in or are interested in learning the results of our previous studies, we aim to provide links to study outcomes on this page. 

Studies can sometimes take many years to conclude and be published, but we feel it is important to reflect on what previous research has achieved. Please click the links below to look at the outcomes of these previous studies:

IDEAL2 Study – Living well and enhancing active life - The IDEAL2 study aimed to provide evidence about living well with dementia, service use and areas of unmet need for people living with dementia. Although the data is still being analysed, they have launched a “Dementia Toolkit” and have a series of publication summaries on their website.

Access the Dementia Toolkit by visiting the Living with Dementia website

Access the key publications by visiting the Ideal Project website

ADAGIO – a feasibility study of a randomised control trial of Interpersonal Counselling compared to Cognitive Behaviour Therapy

Up to one in eight women experience depression during pregnancy. In the UK, low intensity cognitive behavioural therapy (CBT) is the main psychological treatment offered for those with mild or moderate depression and is recommended during the perinatal period, however referral by midwives and take up of treatment by pregnant women is extremely low. Interpersonal Counselling (IPC) is a brief, low-intensity form of Interpersonal Psychotherapy (IPT) that focuses on areas of concern to service users during pregnancy. This was a feasibility study and was not large enough to detect important differences between IPC and perinatal specific CBT. A full-scale trial of IPC for antenatal depression in routine IAPT services is feasible. Read the full article here.

SYMBAD - The SYMBAD trial was a study of mirtazapine for agitation in Dementia. DPT were part of the multi-centre trial to assess the safety, clinical and cost effectiveness of mirtazapine in patients with Alzhiemer’s disease and agitated behaviours. The results of the study have recently been published, finding mirtazapine ineffective at reducing agitation symptoms. Full details available in the Lancet.
 
ThrIVe-B – A feasibility study of an adapted Dialectical Behaviour Therapy to see if it would help people to cope with and manage frequent Bipolar mood swings. It was found that it would be possible to run a larger trial, however they would need to reduce the amount of information delivered in the therapy, and to streamline the number of questionnaires. Further detail is available here.
 
CLIMB - An anonymous online survey of over 29,000 people to establish patient and public views on the sharing of identifiable health data for clinical purposes, and de-identified health data for research within the UK. Over half of the responders supported sharing identifiable health data for clinical purposes across the whole of the UK, and 76% of people wanted it shared across a smaller area. There was also overall support for de-identifiable data sharing with NHS, academic institutions and national research charities for research purposes. Find out more on the CLIMB website.

NHS Check – The UK’s largest survey of the mental health and wellbeing of ALL NHS staff during COVID-19 and beyond.

Visit the NHS Check website to find out more. 

Psychological Impact of COVID 19 – An online survey examining the impact of pandemic mitigation policies, including lockdown relaxation and face coverings, on the mental health of the general population. Results show that relaxation of lockdown, and compulsory face coverings had a positive effect on peoples mental health. Read the full results from Phase 1 of the study. 

SIREN Study – The purpose of this study is to understand whether prior infection with SARS-CoV2 (the virus that causes COVID-19) protects against future infection with the same virus. Regular updates can be found on the Gov website.

Catch US - Our 2018 mapping survey has now closed. A huge thank you to more than 2500 people with ADHD, parents, carers, clinicians and commissioners who have let us know about services for adults with Attention Deficit Hyperactivity Disorder (ADHD) in the UK. Full findings will be made available in 2019. In the meantime please follow us on Twitter #catchusADHD for updates. Further information can be found here

CASIS - A multi-centre cohort study of short term outcomes of hospital treatment for Anorexia Nervosa. You can read the published paper here.

AD Genetics - AD Genetics involved researchers analysing the genome of more than 100,000 people with Alzheimer’s disease, then comparing them with over 600,000 healthy individuals to look for difference in genetic makeup. They identified 42 new genes associated with Alzheimer’s disease. Tje link to news article can be found here.

Brains for Dementia - "Brains for Dementia Research now has 3200 people with and without dementia undergoing regular assessments. We continue to be very grateful to all those who have chosen to support dementia research in this way". Access the Alzheimer’s Society page here.

GERAS - Resource utilisation, costs and clinical outcomes in non-institutionalised patients with Alzheimer’s disease: 18-month UK results from the GERAS observational study. You can find the published article here.

MAGD - Efficacy of Memantine for Agitation in Alzheimer’s Dementia: A Randomised Double-Blind Placebo Controlled Trial. You can find the published article here.

COBRA - Depression is a common, debilitating, and costly disorder. Many patients request psychological therapy, but the best-evidenced therapy—cognitive behavioural therapy (CBT)—is complex and costly. A simpler therapy— behavioural activation (BA)—might be as effective and cheaper than is CBT. We aimed to establish the clinical efficacy and cost-effectiveness of BA compared with CBT for adults with depression. Read the COBRA study here or access the published version by visiting The Lancet website.

Suicide by Middle Aged Men - A national study combining multiple sources of information that provide a detailed account from families, friends and professionals on the stresses men in their mid-life face before they take their lives. Read the published article here.

Study of Suicide in the Criminal Justice System: Nested Case Control - This study aimed to address the current gaps in health information in this area and estimate the relative risk of completing suicide in the broader criminal justice population. Read the study here

Homicide by patients with schizophrenia - The study aimed to: Examine socio-demographic, criminological and clinical characteristics and clinical care of people with schizophrenia who commit homicide compared with control cases with schizophrenia who do not commit homicide. Read the published article here.

STEPWISE Trial - Structured lifestyle education for people with Schizophrenia (STEPWISE): mixed methods process evaluation of a group-based lifestyle education programme to support weight loss in people with schizophrenia. Read the published article here.

Google Calendar as prospective memory aid - Google Calendar: A Memory Aid for People with Prospective Memory Impairment Following Acquired Brain Injury. You can access the published article here.

DiREct - The ‘cohort multiple Randomised Controlled Trial’ (cmRCT) design, has been proposed as a potential solution to poor recruitment into clinical trials and as a way of embedding the principle of research participation into routine health service settings. The DiReCT study used a mixed methods approach to determine the ethical acceptability, the likely overall recruitment yield, the proportion of patients who would consent to being randomly selected to receive new treatments, and the acceptability to clinicians of the cmRCT design. Read the published article here.

Social support for young men leaving care - Research summary: “So what am I?” – Multiple perspectives on young people’s experience of leaving care. Read the published article by visting the Science Direct website

Preferences for Group Arts Therapies - A cross-sectional survey of mental health patients and the general population. The published article can be found here.

Measuring Experiences of Restrictiveness in Secure Forensic Psychiatric Care: Developing a Scale - This study looked to explore how restrictiveness in secure forensic psychiatric care is experienced by patients residing within these care settings. To develop, refine and finalize a scale to measure the latent construct of restrictiveness in secure forensic psychiatric care as experienced by patients. The published article can be found on the Research Gate website

Evaluation Report - Social Care workforce research capacity in the South West

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