The following research studies are currently open for recruitment:
AD-Genetics - A genetics study looking to identify unique genes associated with both Early and Late Onset Alzheimer’s disease. View the patient information sheet for the Early Onset arm here and for the Late Onset arm here
SYMBAD - Clinical trial of Mirtazapine versus placebo in the treatment of agitation for people with dementia. View the patient information sheet here.
Schizophrenia and Psychosis
ADR - Identifying any genetic predispositions for adverse reactions to Clozapine, to develop individualised drug therapy. View the patient information sheet here
PPiP - An observational study collecting demographic and clinical data, in addition to a blood sample. This study aims to understand if some cases of psychiatric illness are caused by the presence of specific antibodies. View the patient information sheet here
SINAPPS2 - Clinical trial of immunotherapy versus placebo for people whose blood tests show that their psychosis is antibody-associated.
SCENE 5 - The aim of the SCENE intervention is to improve patients’ quality of life through enhancing their social networks. The SCENE intervention consists of a number of one-to-one contacts between a patient and a mental health professional over a six-month period. Professionals encourage and help patients to engage in activities of the patients’ choosing that involve social contacts. View the patient information sheet here
Relapse Evaluation using Smart Phone Technology (REST) - This study aims to evaluate the feasibility of predicting relapse in severe mental illness using digital phenotyping data based on smartphone use. View the patient information sheet here
Open Dialogue: Development and Evaluation of a Soicial Network Intervention for Severe Mental Illness (ODDESSI) - The overall aim of the ODDESSI Programme is to assess the effectiveness and cost-effectiveness of Open Dialogue (OD) interventions compared to Treatment as Usual (TAU) for individuals presenting with a mental health crisis to NHS mental health services. For further information please click here
RCT of COPe-support online resource for carers - If you are supporting a loved one affected by psychosis, aged 18 or above, living in England, and enjoy using internet resources, we would like to tell you more about COPe-support. Please visit our website here or click here for further information.
Molecular investigation into Bipolar Disorder (perinatal arm) - This study is looking at factors that make some women with bipolar disorder more likely than others to experience mood episodes in the postpartum period. We hope this study will lead to better prediction and treatments for these episodes. View the patient information sheet here
ADAGIO - A study comparing two talking therapies for women with depression during pregnancy. It aims to improve psychological treatments for depression during pregnancy. Patients are invited to take part during community midwife clinics or ultrasound dating scan clinics. For more information please email firstname.lastname@example.org
National Centre for Mental Health (Perinatal Arm) - This study is trying to understand why some people experience problems with their mental health during the perinatal period. The purpose of this study is to collect information and samples for genetic, biological, psychological and clinical research, to look for genes and other factors which make some people more likely than others to become ill. The study hopes to improve understanding of perinatal mental health and help find better treatments in the future. Please click here for further information.
ASC - The Adult Autism Spectrum Cohort UK, Autism condition in Adulthood - Learning about the lives of adults on the autism spectrum and their relatives in order to create an evidence-based approach to meeting health and social care needs. View the patient information sheet here
IBER - A new psychological intervention for bipolar disorder, called Imagery Based Emotional Regulation (IBER). IBER is a form of cognitive behavioural therapy (CBT), and is specifically aimed at helping people deal with the anxiety that often occurs in people who suffer from bipolar disorder. IBER is a feasibility study with a two-arm randomised parallel controlled trial design. Participants will either carry on with their usual treatment, or be offered IBER in addition to their usual treatment. View the patient information sheet here
BA-BD: Behavioural Activation for Bipolar Depression - A case series evaluation. Behavioural Activation (BA) is an established approach for people with unipolar depression. It helps people re-establish healthier patterns of activity, but thus far there is little research into offering BA to people with bipolar depression. View the patient information sheet here
If you are interested in being involved in participating in research please email email@example.com or phone 01392 674117.