Memory and dementia studies

Digital assessment of auditory perception in dementia (DIADEM) 

We are a team of doctors and researchers, hoping to improve how quickly and accurately people get a dementia diagnosis when they attend a memory clinic.

You can help us if:

  • you have been to a memory clinic to be assessed
  • you have not been to a memory clinic but would like to be a healthy control participant and you are over 55.

Taking park in the DIADEM study would involve one to two hours of your time and will include:

  • memory questions
  • a digital hearing test
  • a blood test

With your consent we will also get some information from your medical recordsa nd then contact you again in 12 months to ask if you are willing to participate in a follow-up session.

For more information please contact a member of our research team on 01392 674117 or email at dpt.diadem@nhs.net

Social cognition and functioning in Alzheimer's dementia (SOCIAL)

The overall aim of this study is to test the hypothesis that impairment in theory of mind is responsible for social behaviour and functioning decline in people with Alzheimerr's dementia.

We are recruiting people with a diagnosis of Alzheimer’s dementia and someone who knows the individual well, for example a friend, partner or family member, to take part in this study.

Participants will complete some questionnaires, watch some videos and answer some questions about them. The person who knows the individual well will also complete some questionnaires about the person with Alzheimer’s dementia.

For more information about taking part, please email dpn-tr.research@nhs.net

RADIO ME

RADIO ME stands for real-time radio remixing for people with mild to moderate dementia who live alone, incorporating agitation reduction and reminders

The purpose of the RADIO ME study is to co-design and develop the RADIO ME system and provide preliminary data on how its effects might be measured. The RADIO ME system will link existing, commercially available technologies, for example sensors or radio, within their intended purpose, so that they can help support the person with dementia by providing reminders and reducing agitation through tailored music.

RADIO ME consists of a Samsung Galaxy smartwatch worn by the people with dementia which measures heart rate and motion and an internet-connected base-station, for example a PC, to play the music and collect the data from the watch.

Anyone with a diagnosis of dementia and self-reported agitation symptoms can take part in this study. For more information about taking part, please email dpn-tr.research@nhs.net

 

COBALT

The aim of this trial is to find out if adding Memantine to AChEI improves overall health and functioning for people with Dementia with Lewy Bodies (DLB) or Parkinsons Disease Dementia (PDD).

We are currently seeking to recruit participants who primarily have a diagnosis of either Dementia with Lewy Bodies or Parkinsons Disease Dementia, and are stable on AcHEi medication. 

To sign up, please email dpt.cobalttrial@nhs.net or contact the research team on either 07773 575471 or 07815 679942 - we will then complete screening and make contact if appropriate.

Click here for further information

Feasibility and acceptability of scaleable tests (FAST) Brain study

This study is designed to determine the feasibility and acceptability of collecting and analysing blood samples as well as cognitive data relevant to dementia risk to inform a larger study. Blood samples from 1000 participants will be taken on two occasions at Wonford House.

During the study visit, the participant will also complete a questionnaire to provide feedback on the study visit as well as the invitation process; they will also be asked to complete cognitive tests online at six monthly intervals (three tests in total).

You can join the study if you:

  • Are willing and able to give informed consent for participation in the study or if assenting then a consultee (nearest of kin or holder of Power of Attorney) is available to make a declaration
  • Are male or female, aged 50 years or over
  • Are within travelling distance to Wonford House
  • Are cognitively healthy OR experiencing subjective or objective pre-dementia cognitive impairment (i.e. subjective memory impairment, SCI or Mild Cognitive Impairment, MCI) OR having a diagnosis of dementia 

For further information please download the poster here or email dpn-tr.research@nhs.net

PROTECT: A longitudinal study of cognition in people over 40 

PROTECT aims to understand how healthy brains age and why people develop dementia. The PROTECT study is run by the University of Exeter and Kings College London, in partnership with the NHS. 

You can join the study if you:

  • Are aged 40 years or older
  • Reside in the UK
  • Do not have a diagnosis of dementia

Once a year, you will be asked to complete a set of questionnaires about yourself, your lifestyle and your health. Each takes an hour or less to complete. You will also be asked to take a series of online tests, to measure changes in brain function.

Sign up online

For more information contact the team at: dpt.researchadmin@nhs.net

Join dementia research

A place to register your interest in dementia research. When you sign up to join dementia research, the information you provide is used to match you to studies you may be able to take part in, both online, nationally and in your local area. The service connects registered volunteers with dementia researchers across the UK who are looking for people to join their studies.

You can sign up as a patient, on behalf of someone else or as a healthcare professional working in dementia healthcare. This resource makes a real difference to dementia research.

Sign up online

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